实操示例 · PDF 转 Word，再译成西班牙语
将 68 页的药品标签转换为 2 页的患者说明单，然后翻译成西班牙语
一家医院药房收到了来自 DailyMed 的 68 页 COVID-19 药物美国标签。他们委托 将其转换为一份 2 页、用通俗英文写成的居家传单，仅使用标签内容，并将所有 40 种患者禁用药物整理在一个表格中。
阅读了标签中写给患者的页面，并将传单写成可打印为两页 Letter 纸的 Word 文件。随后将药剂师的三处修改纳入同一文件，并制作了一份章节、表格及所有剂量均未变动的西班牙语版本。
1FDA 药品说明书：共 68 页，患者信息在第 35 至 41 页
药品说明书：第 35 页，共 68 页PAXLOVID Take-Home Leaflet
- 68需处理的标签页数
- 40表格中的药物，无删减或新增
- 2页 Letter 纸，按打印版面计算
- 0因药剂师编辑而变动的请求 1 行数
打开真实文件
这些是运行过程中的实际文件。请下载并在 Word 中打开它们。
PDF处理前：药物标签68 页 · 来自 DailyMedDOCX请求 1 完成后：传单由标签制作的新 Word 文件DOCX请求 2 完成后：同一传单包含药剂师的两处新增内容DOCX请求 2 完成后：西班牙语版本独立的 Word 文件
文件来源： DailyMed （美国国家医学图书馆），获 FDA 批准的 nirmatrelvir 和 ritonavir 片剂标签，修订于 2026 年 2 月。标签发布者未审阅或背书本范例，且该传单不构成医疗建议：患者应遵循其处方医生的指示。
01 · 初始文件
一份为处方医生编写的标签，其中患者部分位于第 35 至 41 页
68 页内容多数针对医生：剂量表、药物相互作用、临床研究。为患者编写的部分从第 35 页开始，该页同时包含禁止与此药合用的 40 种药物清单，以三栏排列。
肾病患者使用不同的药包：每日两次较低剂量，严重肾病者则使用每日一次且第 1 天安排不同的药包。传单重点在于准确呈现这些差异。
PDF 包含真实文本，因此 直接读取：无需 OCR，无需转换。PDF 本身未经更动。
02 · 请求 1
“根据标签撰写一份 2 页的患者须知传单”
药房的输入内容
Attached is the current PAXLOVID US label from DailyMed (68 pages; the Patient Information leaflet is on pages 35-41). Please write a 2-page take-home leaflet for our COVID-19 patients as a Word document. Use only what the label says, in plain English (short sentences, about 6th-8th grade reading level). Sections, in this order: 1. What PAXLOVID is - including that it is not approved to prevent COVID-19 2. Before you start - kidney or liver problems, HIV-1, pregnancy, breastfeeding, hormonal birth control 3. How to take it - the standard Dose Pack, the two Dose Packs for kidney disease, and what to do if you miss a dose 4. Medicines you must not take with PAXLOVID - all 40 medicines from the 'Do not take PAXLOVID if' list on page 35, in a 3-column table 5. Side effects - the serious ones and the most common ones 6. When to get help right away Letter size, 2 pages maximum.
的操作
- 阅读患者信息页面并归纳各章节所需事实，并标注其来源页码。
- 按要求顺序撰写了六个章节，使用简短句子，并作为 Letter 纸张大小的 Word 文件输出。
- 提供了所有三种药包及其药片：每日两次，每次 2 片粉红药片和 1 片白药片；中度肾病患者为每日两次，每次 1 片粉红药片和 1 片白药片；严重肾病患者则为第 1 天 2 片粉红药片和 1 片白药片，随后每日一次，每次 1 片粉红药片和 1 片白药片，透析日于透析后服用。
- 将 40 种药物放入一个 3 栏表格中，保留标签原文的“midazolam (oral)”及“for pulmonary arterial hypertension”。
- 交稿前检查了打印排版：共两页。
PAXLOVID Take-Home Leaflet
1. What PAXLOVID is
PAXLOVID is a prescription medicine. It is used to treat mild-to-moderate coronavirus disease 2019 (COVID-19) in adults. It is for adults who are at high risk for progression to severe COVID-19. This includes hospitalization or death.
PAXLOVID is not approved to prevent COVID-19. Do not use it as pre-exposure treatment to prevent COVID-19 before exposure. Do not use it as post-exposure treatment to prevent COVID-19 after exposure.
Do not take PAXLOVID if you are allergic to nirmatrelvir, ritonavir, or any of the ingredients in PAXLOVID.
2. Before you start
Tell your care team before you start PAXLOVID if any of these apply to you:
Kidney problems. You may need a different dose or dosing schedule of PAXLOVID.
Liver problems, including hepatitis.
Human Immunodeficiency Virus 1 (HIV-1) infection. PAXLOVID may lead to some HIV-1 medicines not working as well in the future.
Are pregnant or plan to become pregnant. It is not known if PAXLOVID can harm your unborn baby. Tell your healthcare provider right away if you are or if you become pregnant.
Are breastfeeding or plan to breastfeed. PAXLOVID can pass into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with PAXLOVID.
Take combined birth control (hormonal contraceptive). Tell your healthcare provider. PAXLOVID may affect how your hormonal contraceptives work. Females who are able to become pregnant should use another effective alternative form of contraception or an additional barrier method of contraception during treatment with PAXLOVID.
3. How to take it
PAXLOVID consists of 2 medicines: nirmatrelvir tablets and ritonavir tablets. The 2 medicines are taken together for 5 days.
Take PAXLOVID with or without food. Swallow the tablets whole. Do not chew, break, or crush the tablets.
Standard Dose Pack — 300 mg; 100 mg: Each dose contains 3 tablets taken together twice daily, in the morning and at bedtime. Take the 2 pink nirmatrelvir tablets and 1 white to off-white ritonavir tablet together.
Kidney Dose Pack — 150 mg; 100 mg: Each dose contains 2 tablets taken together twice daily, in the morning and at bedtime. Take the 1 pink nirmatrelvir tablet and 1 white ritonavir tablet together.
Severe kidney once-daily pack — 300 mg; 100 mg (Day 1) and 150 mg; 100 mg (Days 2-5): Each dose is taken together once daily. Day 1 (First Day): Take the 2 pink nirmatrelvir tablets and 1 white ritonavir tablet together (Blue part of the blister card). Days 2-5: Take the 1 pink nirmatrelvir tablet and 1 white ritonavir tablet together (Pink part of the blister card). On days of dialysis, take PAXLOVID after receiving dialysis.
If you miss a dose within 8 hours, take it as soon as you remember. If you miss a dose by more than 8 hours, skip it and take the next dose at your regular time. Do not take 2 doses of PAXLOVID at the same time.
4. Medicines you must not take with PAXLOVID
Warning: PAXLOVID can interact with other medicines causing severe or life-threatening side effects or death. Do not take any medicine in this table with PAXLOVID.
第 2 页
| Medicine A–M | Medicine N–R | Medicine S–V |
|---|---|---|
| alfuzosin | ivabradine | ranolazine |
| amiodarone | lomitapide | rifampin |
| apalutamide | lovastatin | rifapentine |
| carbamazepine | lumacaftor/ivacaftor | St. John’s Wort (hypericum perforatum) |
| colchicine | lurasidone | sildenafil (Revatio ® ) for pulmonary arterial hypertension |
| dihydroergotamine | methylergonovine | silodosin |
| dronedarone | midazolam (oral) | simvastatin |
| eletriptan | naloxegol | suzetrigine |
| enzalutamide | phenobarbital | tolvaptan |
| eplerenone | phenytoin | triazolam |
| ergotamine | pimozide | ubrogepant |
| finerenone | primidone | voclosporin |
| flecainide | propafenone | |
| flibanserin | quinidine |
5. Side effects
PAXLOVID can cause side effects. Some are serious. Others are more common and less serious.
5.1 Serious allergic reactions
Allergic reactions have happened during treatment with PAXLOVID. These include severe allergic reactions (anaphylaxis). Signs of an allergic reaction are:
skin rash
hives
blisters or peeling skin
painful sores or ulcers in the mouth, nose, throat or genital area
swelling of the mouth, lips, tongue or face
trouble swallowing or breathing
throat tightness
hoarseness
5.2 Liver problems
Liver problems can happen during treatment with PAXLOVID. Signs of liver problems are:
loss of appetite
yellowing of your skin and the white of eyes
dark-colored urine
pale colored stools
itchy skin
stomach-area (abdominal) pain
5.3 Common side effects
The most common side effects of PAXLOVID include altered sense of taste and diarrhea. The altered taste may be metallic taste. It may be bitter taste.
Other possible side effects include headache, vomiting, stomach (abdominal) pain, nausea, high blood pressure, and feeling generally unwell.
6. When to get help right away
Stop taking PAXLOVID and get emergency help right away if you get any signs of an allergy. You can find these signs in Side effects. Do not keep taking PAXLOVID after allergy signs start.
Call your healthcare provider right away if you get any signs of liver problems during treatment with PAXLOVID. You can find these signs in Side effects.
If you take too much PAXLOVID, call your healthcare provider or go to the nearest hospital emergency room right away.
Talk to your healthcare provider if you do not feel better after 5 days. Talk to your healthcare provider also if you feel worse after 5 days.
我们将其与标签进行对照检查： 每种剂量和药包均符合标签第 1 页的摘要及第 38、39 页的药包图示；漏服规则采用标签规定的 8 小时；表格正好包含第 35 页的 40 种药物，无遗漏或新增；按 Word 的规则及 LibreOffice 排版，均可打印为两页 Letter 纸。
03 · 请求 2
“三次药剂师编辑，然后制作西班牙语版本”
药房的输入内容
Pharmacist review of the English leaflet - please edit that same file: 1. Add a shaded box at the very top that reads exactly: 'Tell every doctor and pharmacist you are taking PAXLOVID.' 2. In 'How to take it', add that the tablets must be swallowed whole (do not chew, break or crush them) and can be taken with or without food. 3. Directly under the medicines table, add: 'This is not a complete list. Ask your pharmacist before you start any new medicine.' Leave everything else as it is. Then make a Spanish copy of the updated leaflet as a separate Word file: same sections, same table, still 2 pages. Use 'usted' throughout, keep the brand name PAXLOVID and the drug names unchanged, and keep every dose and number exactly as in the English.
的操作
- 打开先前制作的传单并对同一文件进行编辑。
- 在最顶部增加了一个阴影方框，内文逐字照录。
- 保留“如何服用”部分：传单已说明须将药片整粒吞服，且可随餐或空腹服用。
- 在表格正下方增加了一行“这并非完整清单”，置于表格之外。
- 从已编辑的传单制作出独立的 Word 文件作为西班牙语版本：全文使用“usted”（尊称），药物名称及所有数字与英文版相同。
于请求 2 中新增Tell every doctor and pharmacist you are taking PAXLOVID.
PAXLOVID Take-Home Leaflet
1. What PAXLOVID is
PAXLOVID is a prescription medicine. It is used to treat mild-to-moderate coronavirus disease 2019 (COVID-19) in adults. It is for adults who are at high risk for progression to severe COVID-19. This includes hospitalization or death.
PAXLOVID is not approved to prevent COVID-19. Do not use it as pre-exposure treatment to prevent COVID-19 before exposure. Do not use it as post-exposure treatment to prevent COVID-19 after exposure.
Do not take PAXLOVID if you are allergic to nirmatrelvir, ritonavir, or any of the ingredients in PAXLOVID.
2. Before you start
Tell your care team before you start PAXLOVID if any of these apply to you:
Kidney problems. You may need a different dose or dosing schedule of PAXLOVID.
Liver problems, including hepatitis.
Human Immunodeficiency Virus 1 (HIV-1) infection. PAXLOVID may lead to some HIV-1 medicines not working as well in the future.
Are pregnant or plan to become pregnant. It is not known if PAXLOVID can harm your unborn baby. Tell your healthcare provider right away if you are or if you become pregnant.
Are breastfeeding or plan to breastfeed. PAXLOVID can pass into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with PAXLOVID.
Take combined birth control (hormonal contraceptive). Tell your healthcare provider. PAXLOVID may affect how your hormonal contraceptives work. Females who are able to become pregnant should use another effective alternative form of contraception or an additional barrier method of contraception during treatment with PAXLOVID.
3. How to take it
PAXLOVID consists of 2 medicines: nirmatrelvir tablets and ritonavir tablets. The 2 medicines are taken together for 5 days.
Take PAXLOVID with or without food. Swallow the tablets whole. Do not chew, break, or crush the tablets.
Standard Dose Pack — 300 mg; 100 mg: Each dose contains 3 tablets taken together twice daily, in the morning and at bedtime. Take the 2 pink nirmatrelvir tablets and 1 white to off-white ritonavir tablet together.
Kidney Dose Pack — 150 mg; 100 mg: Each dose contains 2 tablets taken together twice daily, in the morning and at bedtime. Take the 1 pink nirmatrelvir tablet and 1 white ritonavir tablet together.
Severe kidney once-daily pack — 300 mg; 100 mg (Day 1) and 150 mg; 100 mg (Days 2-5): Each dose is taken together once daily. Day 1 (First Day): Take the 2 pink nirmatrelvir tablets and 1 white ritonavir tablet together (Blue part of the blister card). Days 2-5: Take the 1 pink nirmatrelvir tablet and 1 white ritonavir tablet together (Pink part of the blister card). On days of dialysis, take PAXLOVID after receiving dialysis.
If you miss a dose within 8 hours, take it as soon as you remember. If you miss a dose by more than 8 hours, skip it and take the next dose at your regular time. Do not take 2 doses of PAXLOVID at the same time.
4. Medicines you must not take with PAXLOVID
Warning: PAXLOVID can interact with other medicines causing severe or life-threatening side effects or death. Do not take any medicine in this table with PAXLOVID.
第 2 页
| Medicine A–M | Medicine N–R | Medicine S–V |
|---|---|---|
| alfuzosin | ivabradine | ranolazine |
| amiodarone | lomitapide | rifampin |
| apalutamide | lovastatin | rifapentine |
| carbamazepine | lumacaftor/ivacaftor | St. John’s Wort (hypericum perforatum) |
| colchicine | lurasidone | sildenafil (Revatio ® ) for pulmonary arterial hypertension |
| dihydroergotamine | methylergonovine | silodosin |
| dronedarone | midazolam (oral) | simvastatin |
| eletriptan | naloxegol | suzetrigine |
| enzalutamide | phenobarbital | tolvaptan |
| eplerenone | phenytoin | triazolam |
| ergotamine | pimozide | ubrogepant |
| finerenone | primidone | voclosporin |
| flecainide | propafenone | |
| flibanserin | quinidine |
于请求 2 中新增This is not a complete list. Ask your pharmacist before you start any new medicine.
5. Side effects
PAXLOVID can cause side effects. Some are serious. Others are more common and less serious.
5.1 Serious allergic reactions
Allergic reactions have happened during treatment with PAXLOVID. These include severe allergic reactions (anaphylaxis). Signs of an allergic reaction are:
skin rash
hives
blisters or peeling skin
painful sores or ulcers in the mouth, nose, throat or genital area
swelling of the mouth, lips, tongue or face
trouble swallowing or breathing
throat tightness
hoarseness
5.2 Liver problems
Liver problems can happen during treatment with PAXLOVID. Signs of liver problems are:
loss of appetite
yellowing of your skin and the white of eyes
dark-colored urine
pale colored stools
itchy skin
stomach-area (abdominal) pain
5.3 Common side effects
The most common side effects of PAXLOVID include altered sense of taste and diarrhea. The altered taste may be metallic taste. It may be bitter taste.
Other possible side effects include headache, vomiting, stomach (abdominal) pain, nausea, high blood pressure, and feeling generally unwell.
6. When to get help right away
Stop taking PAXLOVID and get emergency help right away if you get any signs of an allergy. You can find these signs in Side effects. Do not keep taking PAXLOVID after allergy signs start.
Call your healthcare provider right away if you get any signs of liver problems during treatment with PAXLOVID. You can find these signs in Side effects.
If you take too much PAXLOVID, call your healthcare provider or go to the nearest hospital emergency room right away.
Talk to your healthcare provider if you do not feel better after 5 days. Talk to your healthcare provider also if you feel worse after 5 days.
Informe a cada médico y farmacéutico que usted está tomando PAXLOVID.
Folleto de PAXLOVID para llevar a casa
1. Qué es PAXLOVID
PAXLOVID es un medicamento recetado. Se usa para tratar la enfermedad por coronavirus 2019 (COVID-19) de leve a moderada en adultos. Es para adultos que tienen un riesgo alto de progresión a COVID-19 grave. Esto incluye hospitalización o muerte.
PAXLOVID no está aprobado para prevenir la COVID-19. No lo use como tratamiento previo a la exposición para prevenir la COVID-19 antes de la exposición. No lo use como tratamiento posterior a la exposición para prevenir la COVID-19 después de la exposición.
No tome PAXLOVID si usted es alérgico a nirmatrelvir, ritonavir o a cualquiera de los ingredientes de PAXLOVID.
2. Antes de que usted empiece
Informe a su equipo de atención médica antes de empezar a tomar PAXLOVID si alguna de estas situaciones aplica a usted:
Problemas de riñón. Es posible que usted necesite una dosis o un horario de dosis diferente de PAXLOVID.
Problemas de hígado, incluida la hepatitis.
Infección por el virus de la inmunodeficiencia humana 1 (HIV-1). PAXLOVID puede hacer que algunos medicamentos contra el HIV-1 no funcionen tan bien en el futuro.
Si usted está embarazada o planea quedar embarazada. No se sabe si PAXLOVID puede dañar a su bebé por nacer. Informe a su proveedor de atención médica de inmediato si usted está embarazada o si queda embarazada.
Si usted está amamantando o planea amamantar. PAXLOVID puede pasar a su leche materna. Hable con su proveedor de atención médica sobre la mejor forma de alimentar a su bebé durante el tratamiento con PAXLOVID.
Si usted toma anticonceptivos combinados (anticonceptivo hormonal). Informe a su proveedor de atención médica. PAXLOVID puede afectar cómo funcionan sus anticonceptivos hormonales. Las mujeres que pueden quedar embarazadas deben usar otra forma anticonceptiva alternativa eficaz o un método anticonceptivo de barrera adicional durante el tratamiento con PAXLOVID.
3. Cómo lo debe tomar usted
PAXLOVID consta de 2 medicamentos: tabletas de nirmatrelvir y tabletas de ritonavir. Los 2 medicamentos se toman juntos durante 5 días.
Tome PAXLOVID con o sin alimentos. Trague las tabletas enteras. No las mastique, parta ni triture.
Paquete de dosis estándar — 300 mg; 100 mg: Cada dosis contiene 3 tabletas que se toman juntas dos veces al día, por la mañana y antes de acostarse. Tome las 2 tabletas rosas de nirmatrelvir y 1 tableta de ritonavir de blanca a blanquecina juntas.
Paquete de dosis para el riñón — 150 mg; 100 mg: Cada dosis contiene 2 tabletas que se toman juntas dos veces al día, por la mañana y antes de acostarse. Tome 1 tableta rosa de nirmatrelvir y 1 tableta blanca de ritonavir juntas.
Paquete de una vez al día para riñón grave — 300 mg; 100 mg (Día 1) y 150 mg; 100 mg (Días 2-5): Cada dosis se toma junta una vez al día. Día 1 (Primer día): Tome las 2 tabletas rosas de nirmatrelvir y 1 tableta blanca de ritonavir juntas (parte azul del blíster). Días 2-5: Tome 1 tableta rosa de nirmatrelvir y 1 tableta blanca de ritonavir juntas (parte rosa del blíster). En los días de diálisis, tome PAXLOVID después de recibir la diálisis.
Si olvida una dosis y han pasado menos de 8 horas, tómela tan pronto como lo recuerde. Si han pasado más de 8 horas, omita esa dosis y tome la siguiente dosis a su hora habitual. No tome 2 dosis de PAXLOVID al mismo tiempo.
4. Medicamentos que usted no debe tomar con PAXLOVID
Advertencia: PAXLOVID puede interactuar con otros medicamentos y causar efectos secundarios graves o potencialmente mortales, o la muerte. No tome ningún medicamento de esta tabla con PAXLOVID.
第 2 页
| Medicamentos A–M | Medicamentos N–R | Medicamentos S–V |
|---|---|---|
| alfuzosin | ivabradine | ranolazine |
| amiodarone | lomitapide | rifampin |
| apalutamide | lovastatin | rifapentine |
| carbamazepine | lumacaftor/ivacaftor | St. John’s Wort (hypericum perforatum) |
| colchicine | lurasidone | sildenafil (Revatio ® ) para la hipertensión arterial pulmonar |
| dihydroergotamine | methylergonovine | silodosin |
| dronedarone | midazolam (oral) | simvastatin |
| eletriptan | naloxegol | suzetrigine |
| enzalutamide | phenobarbital | tolvaptan |
| eplerenone | phenytoin | triazolam |
| ergotamine | pimozide | ubrogepant |
| finerenone | primidone | voclosporin |
| flecainide | propafenone | |
| flibanserin | quinidine |
Esta no es una lista completa. Pregunte a su farmacéutico antes de empezar a tomar cualquier medicamento nuevo.
5. Efectos secundarios
PAXLOVID puede causar efectos secundarios. Algunos son graves. Otros son más comunes y menos graves.
5.1 Reacciones alérgicas graves
Se han producido reacciones alérgicas durante el tratamiento con PAXLOVID. Estas incluyen reacciones alérgicas graves (anafilaxia). Los signos de una reacción alérgica son:
erupción en la piel
ronchas
ampollas o descamación de la piel
llagas o úlceras dolorosas en la boca, la nariz, la garganta o la zona genital
hinchazón de la boca, los labios, la lengua o la cara
dificultad para tragar o respirar
opresión en la garganta
ronquera
5.2 Problemas del hígado
Pueden presentarse problemas del hígado durante el tratamiento con PAXLOVID. Los signos de problemas del hígado son:
pérdida del apetito
color amarillento en su piel y en la parte blanca de sus ojos
orina de color oscuro
heces de color pálido
picazón en la piel
dolor en el área del estómago (abdominal)
5.3 Efectos secundarios comunes
Los efectos secundarios más comunes de PAXLOVID incluyen alteración del sentido del gusto y diarrea. La alteración del gusto puede ser un sabor metálico. Puede ser un sabor amargo.
Otros posibles efectos secundarios incluyen dolor de cabeza, vómitos, dolor de estómago (abdominal), náuseas, presión arterial alta y sensación general de malestar.
6. Cuándo debe usted buscar ayuda de inmediato
Deje de tomar PAXLOVID y busque ayuda de emergencia de inmediato si usted presenta algún signo de alergia. Usted puede encontrar estos signos en Efectos secundarios. No siga tomando PAXLOVID después de que comiencen los signos de alergia.
第 3 页 · 超过 2 页上限
Llame a su proveedor de atención médica de inmediato si usted presenta algún signo de problemas del hígado durante el tratamiento con PAXLOVID. Usted puede encontrar estos signos en Efectos secundarios.
Si usted toma demasiado PAXLOVID, llame a su proveedor de atención médica o vaya a la sala de emergencias del hospital más cercano de inmediato.
Hable con su proveedor de atención médica si usted no se siente mejor después de 5 días. Hable con su proveedor de atención médica también si usted se siente peor después de 5 días.
我们检查了： 与请求 1 的唯一差异为方框及表格下方的一行字；英文版仍为两页；西班牙语版本包含相同的 40 种药物、相同的剂量（150 mg、100 mg、5 días、8 horas），且未使用“tú”（非正式的“你”）形式。
值得了解： 西班牙语文字比英语长。按照 Word 的规则排版，西班牙语版本会多出六行到第三页（LibreOffice 排版则可容纳在两页内）。 的回复如实说明了这一点，而非声称只有两页；在 Word 中删减一句话或调整页边距即可恢复为两页。
从长篇标签到患者可读的传单
大多数 AI 工具仅在聊天中撰写摘要。 将传单编写为真实的 Word 文件，检查打印页数，将药剂师的编辑并入同一文件中，并提供一份剂量完全不变的译本。
继续阅读
